神經(jīng)肽的目的是快速發(fā)表關(guān)于肽在中樞和外周神經(jīng)系統(tǒng)中的結(jié)構(gòu)、分布、作用和功能的原始研究和綜述文章。這一領(lǐng)域的研究活動(dòng)激增,導(dǎo)致許多天然內(nèi)源性肽的鑒定,這些肽作為神經(jīng)遞質(zhì)、神經(jīng)調(diào)節(jié)劑或營(yíng)養(yǎng)因子,介導(dǎo)神經(jīng)系統(tǒng)功能。越來越多的神經(jīng)肽受體的非肽配體被開發(fā)出來,它們?cè)陔哪芟到y(tǒng)中起激動(dòng)劑或拮抗劑的作用。該雜志提供了一個(gè)獨(dú)特的機(jī)會(huì),整合了涉及所有神經(jīng)肽研究的許多學(xué)科。該雜志發(fā)表的文章涉及神經(jīng)肽領(lǐng)域的各個(gè)方面,特別強(qiáng)調(diào)肽表達(dá)的基因調(diào)控、肽受體亞型、神經(jīng)肽和肽受體基因突變的轉(zhuǎn)基因和敲除小鼠、神經(jīng)解剖學(xué)、生理學(xué)、行為學(xué)、神經(jīng)營(yíng)養(yǎng)因子、臨床前藥物評(píng)價(jià)、臨床研究和臨床試驗(yàn)。原始論文占主導(dǎo)地位。手稿可以是任何長(zhǎng)度,但必須是完整的研究報(bào)告;不接受初步通訊。歡迎評(píng)論文章和假設(shè)論文,并將以與實(shí)驗(yàn)論文相同的方式進(jìn)行評(píng)估。建議打算提交評(píng)論的作者與編輯溝通他們的意圖,以避免可能的重復(fù)。
The aim of Neuropeptides is the rapid publication of original research and review articles, dealing with the structure, distribution, actions and functions of peptides in the central and peripheral nervous systems. The explosion of research activity in this field has led to the idenfication of numerous naturally occurring endogenous peptides which act as neurotransmitters, neuromodulators, or trophic factors, to mediate nervous system functions. Increasing numbers of non-peptide ligands of neuropeptide receptors have been developed, which act as agonists or antagonists in peptidergic systems. The journal provides a unique opportunity of integrating the many disciplines involved in all neuropeptide research. The journal publishes articles on all aspects of the neuropeptide field, with particular emphasis on gene regulation of peptide expression, peptide receptor subtypes, transgenic and knockout mice with mutations in genes for neuropeptides and peptide receptors, neuroanatomy, physiology, behaviour, neurotrophic factors, preclinical drug evaluation, clinical studies, and clinical trials. Original papers predominate. Manuscripts may be of any length, but must be complete studies; preliminary communications are not accepted. Review articles and hypothesis papers are welcomed, and will be evaluated in the same way as experimental papers. Authors intending to submit a review are advised to communicate their intentions to the Editors, to avoid possible duplication.
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