《自然遺傳學》發表了最高質量的遺傳學研究。它包括對人類和植物性狀以及其他模型生物體的遺傳和功能基因組研究。目前的研究重點是常見和復雜疾病的遺傳基礎，以及通過實驗擾動研究基因網絡的功能機制、結構和進化。綜合遺傳主題包括但不限于:人類疾病病理學中的基因簡單和復雜遺傳性狀的分子分析癌癥遺傳學農業基因組學發育遺傳學基因表達的調控變異從基因組數據中提取功能的策略和技術藥物基因組學基因組進化

Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.Integrative genetic topics comprise, but are not limited to:Genes in the pathology of human diseaseMolecular analysis of simple and complex genetic traitsCancer geneticsAgricultural genomicsDevelopmental geneticsRegulatory variation in gene expressionStrategies and technologies for extracting function from genomic dataPharmacological genomicsGenome evolution