《癌癥研究》在基礎研究、臨床研究、轉化研究、流行病學研究和預防研究的所有領域發表重要的原創研究，致力于癌癥和癌癥相關生物醫學科學的研究。科學主題包括:生物化學;化學、物理和病毒致癌和誘變;臨床調查，包括臨床試驗;內分泌學;流行病學和預防;實驗治療學;免疫學和免疫治療包括生物治療;分子生物學與遺傳學;放射生物學和放射腫瘤學;腫瘤生物學;和病毒學。因此，它的出版范圍涵蓋了癌癥研究的所有子領域。論文經過嚴格審查，只有那些報告新穎、及時、有意義的研究結果并符合高科學價值標準的論文才會被接受發表。

Cancer Research publishes significant, original studies in all areas of basic, clinical, translational, epidemiological, and prevention research devoted to the study of cancer and cancer-related biomedical sciences. Scientific topics include: biochemistry; chemical, physical, and viral carcinogenesis and mutagenesis; clinical investigations including clinical trials; endocrinology; epidemiology and prevention; experimental therapeutics; immunology and immunotherapy including biological therapy; molecular biology and genetics; radiobiology and radiation oncology; tumor biology; and virology. Thus its publication scope covers all subfields of cancer research. Papers are stringently reviewed and only those that report results of novel, timely, and significant research and meet high standards of scientific merit will be accepted for publication.