當代生物醫(yī)學研究正處于一個時代的門檻，在這個時代，生理和病理過程可以用越來越精確和機械的術語來分析。生物學從一門以描述性為主的現(xiàn)象學學科，轉變?yōu)橐婚T可理解和可預測地操縱調控原則的學科，為癌癥研究和尋找這種疾病的有效治療方式帶來了一個新的維度。癌癥和轉移綜述為這些具有挑戰(zhàn)性的進展提供了一個批判性綜述和討論的論壇。每一期的《癌癥與轉移評論》都有一個特定的主題或主題，并將包含5到7個不同的貢獻。此外，一個介紹性前言包括從一個人誰是在該領域的杰出覆蓋。主題和供稿人是由總編與編輯咨詢委員會的不同成員協(xié)商后選定的。特別強調與癌癥轉移和腫瘤進展的分子和細胞生物學以及轉移性疾病的治療有關的主題。偶爾的問題將致力于對一種特定類型的癌癥進行深入的臨床和生物學分析。該雜志的一項主要功能是回顧生物學和惡性疾病治療方面一些更重要和更有趣的最新進展，并強調新的和有希望的方向，無論是技術上還是概念上。我們鼓勵投稿者回顧他們的個人作品，并進行猜測。

Contemporary biomedical research is on the threshold of an era in which physiological and pathological processes can be analyzed in increasingly precise and mechanistic terms. The transformation of biology from a largely descriptive phenomenological discipline to one in which the regulatory principles can be understood and manipulated with predictability brings a new dimension to the study of cancer and the search for effective therapeutic modalities for this disease. Cancer and Metastasis Reviews provides a forum for critical review and discussion of these challenging developments. Each issue of Cancer and Metastasis Reviews is devoted to a particular theme or topic and will contain from five to seven different contributions. In addition an introductory preface is included from an individual who is distinguished in the field to be covered. The topics and contributors are chosen by the Editor-in-Chief after consultation with various members of the Editorial Advisory Board. Special emphasis is placed on subjects which are of relevance to the molecular and cellular biology of cancer metastasis and tumor progression as well as to the treatment of metastatic disease. Occasional issues will be devoted to an in-depth clinical and biological analysis of a particular type of cancer. A major function of the journal is to review some of the more important and interesting recent developments in the biology and treatment of malignant disease as well as to highlight new and promising directions be they technological or conceptual. Contributors are encouraged to review their personal work and be speculative.